Dr. Alina Akhunova: K-State Integrated Genomics Facility: Wheat Genomics and Beyond
K-State Integrated Genomics Facility (IGF) uses modern genomics approaches to characterize genomes of organisms having importance for ecology, agronomy, veterinary medicine and basic biology. Our project portfolio includes genomics studies ranging from customized small-scale projects focused on specific biological questions to large-scale whole-genome sequencing, RNA-seq, environmental eDNA-seq and targeted or low-coverage re-sequencing of complex genomes. We have performed targeted re-sequencing of natural and chemically mutagenized populations of wheat and barley generating catalogs of mutations in genic and regulatory regions of their genomes for functional and gene mapping studies. The approach developed at IGF for detecting gene editing events in the wheat genome allows us to simultaneously screen for up to 1,000 edited gene targets in large populations of transgenic plants in a single instrument run. We applied comparative whole genome sequencing of natural and chemically mutagenized strains of stem rust to identify the first rust avirulence gene responsible for triggering defense response by a Ug99 effective stem rust resistance gene. I will use these and other case studies as examples to demonstrate the capabilities of IGF genomics instrumentation and present its application for genome analyses. Read Abstract (PDF).
Thursday, September 19, 2019 at 3:45pm
Throckmorton Plant Sciences Center, 4031
( Map)
1712 Claflin Rd Manhattan KS 66506-5500
- Event Type
- Department
- Plant Pathology, Department of
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